The Digest.

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The Peter Attia Drive summaries

Every long episode from The Peter Attia Drive, read in minutes: the key takeaways, the chapters, and a digest of the whole conversation. Expert insight on health, performance, longevity, critical thinking, and pursuing excellence. Dr. Peter Attia (Stanford/Hopkins/NIH-trained MD) talks with leaders in their fields.

#409 ‒ Inside modern drug development: the science, economics, and regulatory hurdles behind bringing new medicines to patients | Lloyd Klickstein, M.D., Ph.D.

Dr. Lloyd Klickstein, a physician-scientist and drug developer, unpacks the complex journey of discovering and developing new medicines, using the muscle-preserving drug bimagrumab as a case study to reveal the science, economics, and regulatory challenges behind modern drug development.

September 28, 2026

#407 ‒ Preventing cardiovascular and Alzheimer's disease: lowering LDL early, APOE4, and promising new therapies | Michael Davidson, M.D.

Dr. Michael Davidson, a cardiologist and lipidologist, discusses the critical role of early LDL lowering in preventing cardiovascular disease, the nuanced understanding of APOE4 in Alzheimer's, and the potential of emerging therapies like obicetrapib and clotho.

September 14, 2026

Blood pressure: how to measure, manage, and treat high blood pressure (AMA #48 rebroadcast)

In this AMA, Peter Attia and his co-host discuss everything you need to know about blood pressure, including how to measure it, the consequences of high blood pressure, and how to manage and treat it through lifestyle and medication.

September 7, 2026

#406 ‒ Migraine, cluster headache, and tension headache: symptoms, causes, prevention, and treatment | Brian Grosberg, M.D.

Dr. Brian Grosberg, a leading headache specialist, discusses the nuances of migraine, cluster headaches, and tension headaches, covering symptoms, causes, prevention, and the latest treatment strategies.

August 31, 2026

#405 ‒ AMA #88: Metabolic liver health: how to assess risk, catch dysfunction early, and prevent or reverse liver disease

Dr. Peter Attia discusses metabolic liver health, including how to assess risk, catch dysfunction early, and prevent or reverse liver disease.

August 24, 2026

#404 ‒ Mental health beyond neurotransmitters: the role of hormones in psychiatry, why symptom reduction isn't enough, and the future of psychedelic therapies | Linus Abrams, M.D.

Dr. Linus Abrams, a psychiatrist with 35 years of clinical experience, discusses the limitations of traditional psychiatry, the crucial role of hormones in mental health, and the potential future of psychedelic therapies.

August 17, 2026

#403 ‒ Peptides: separating scientific promise from marketing hype

Peter Attia and Nick Stenson discuss the current landscape of peptides, separating scientific promise from marketing hype, and providing a framework for evaluating any peptide you might encounter.

August 10, 2026

#402 ‒ NMR blood analysis: how heart disease risk, insulin resistance, inflammation, and mortality risk can be assessed from a single blood sample | Jim Otvos, Ph.D.

Jim Otvos, Ph.D., is a biophysical chemist who pioneered the use of nuclear magnetic resonance (NMR) spectroscopy to measure lipoprotein particles from plasma. He returns to the podcast to discuss how NMR technology can be used to assess heart disease risk, insulin resistance, inflammation, and mortality risk from a single blood sample.

August 3, 2026

#401 ‒ How curiosity transforms medicine: extraordinary discoveries that changed modern healthcare

Peter Attia explores how curiosity-driven basic research, often appearing medically irrelevant at first, has fundamentally transformed modern healthcare, leading to groundbreaking discoveries like GFP, statins, ACE inhibitors, PCR, CRISPR, and GLP-1 agonists.

July 27, 2026