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a16z Podcast summaries

Every long episode from a16z Podcast, read in minutes: the key takeaways, the chapters, and a digest of the whole conversation. The a16z Show discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This show is produced by Andreessen Horowitz (aka “a16…

Beyond the God Model | Alex Atallah & Amjad Masad

Alex Atallah of OpenRouter and Amjad Masad of Replit explore the future of AI through specialized models, neurodiversity, and enterprise independence.

October 3, 2026

AI Can Write Code. Why Isn’t Software Better?

Diogo Almeida, founder of TypeSafe AI, reimagines AI's role in software by introducing JEV, a new primitive that embeds intelligence within software to enable true automation beyond faster coding.

September 28, 2026

Building a Team at AI Speed | Harvey’s Maggie Landers

Maggie Landers, VP of Talent at Harvey, shares how the company hires and scales culture at AI speed while transforming the legal industry.

September 27, 2026

AI Safety Language Is Destroying the Debate | Steven Sinofsky

Steven Sinofsky, former Microsoft Windows President and A16Z board partner, argues that the current language around AI safety is making the technology harder to understand and hindering productive debate.

September 21, 2026

Nas, Grandmaster Caz, Steve Stoute & Ben Horowitz on Paying Hip-Hop’s Pioneers Their Due

Nas, Grandmaster Caz, Steve Stoute, and Ben Horowitz discuss the Payday Full Foundation's mission to honor hip-hop pioneers by providing both financial support and recognition, highlighting the industry's historical oversight and the profound impact this initiative has on artists' lives and the culture at large.

September 20, 2026

What Makes a Consumer AI Product Stick? | Josh Elman

A16Z partner Josh Elman joins new economies to discuss what it takes to build a lasting consumer product in the AI era. Josh explains why the best products start by doing one thing exceptionally well, become a habit, and then earn the right to do more.

September 19, 2026

Databricks CEO on AI Pacing, Cyber Risk, and the Enterprise

Databricks CEO Ali Ghodsi joins a16z's Martin Casado and Sarah Wang to discuss what's holding back AI adoption, why the answer may have less to do with building smarter models, and more to do with giving them the right context.

September 18, 2026

The Next Frontier of AI Video Is Control

Falco co-founder Gokcen Gorkem and Head of Engineering Batuhan Taskaya discuss H3 Max, a new generative video model, and the rapidly changing generative video stack.

September 17, 2026

The AI-Native CRM

Lightfield CEO Keith Peiris discusses his journey from building Tome to a $47M Series A for his new AI-native CRM, and how AI is changing the way companies build and operate.

September 16, 2026

The Age of Body Futurism | Ruby Justice Thelot

Academic and cyber-ethnographer Ruby Justice Thelot joins Elena Berger to unpack the gaps between what's happening online and what people are actually doing in the real world, using today's wellness and optimization culture as a case study.

September 15, 2026

Greg Brockman on Why OpenAI Says We’re Entering the AGI Era

OpenAI co-founder and President Greg Brockman discusses why he believes we are now in the AGI era, the challenges of distributing AI's power, and how AI can fundamentally change our relationship with software and employment.

September 14, 2026

World Models, Robotics, and the Future of 3D AI

World Labs co-founder Justin Johnson discusses Atlas, the world's first multimodal world model, and its applications in generating, simulating, and reconstructing physical environments for industries like gaming, VFX, and robotics.

September 13, 2026

Why Companies Are Becoming a Series of Loops | Anish Acharya on Lenny’s Podcast

Anish Acharya, General Partner at a16z, discusses why companies are becoming a series of loops, how AI amplifies human agency, and why we should be more ambitious about what this technology makes possible.

September 12, 2026

What It Takes to Build a Startup | Andrew Chen & Matt Perault

Andrew Chen, General Partner at Andreessen Horowitz, and Speedrun lead, sits down with Matt Perault to discuss the challenges and realities of building a startup from day one, focusing on the "little tech" teams and the regulatory landscape they navigate.

September 11, 2026

How AI Is Rewriting the Power Law of Venture Capital

A16z's Jim Breyer and David George discuss how AI is fundamentally changing venture capital, from asset allocation and portfolio construction to market dynamics and the definition of a "winner."

September 10, 2026

Who Grades the AI Models? | Ben Horowitz & Rayan Krishnan

Val.ai founder and CEO Reyan Krishnan joins a16z’s Ben Horowitz and Jennifer Li to discuss the increasingly difficult problem of measuring AI, why public benchmarks can give a distorted picture of model capabilities, why independent evaluation matters, and what it takes to test a new model in a few hours before it launches.

September 9, 2026

OpenAI Researchers on the Future of Mathematical Reasoning

OpenAI mathematicians Metaswani and Mark Salky discuss how AI is beginning to make progress on mathematical problems that have resisted humans for decades, and what that means for the future of mathematical practice.

September 8, 2026

Your AI Doctor Is Coming | Julie Yoo

Julie Yoo, a general partner at Andreessen Horowitz, explains why healthcare is uniquely positioned to benefit from AI, how the industry's slow adoption of technology is now an advantage, and where she sees the biggest opportunities for founders.

September 6, 2026

Aaron Levie on Why Open AI Wins

Aaron Levie, co-founder and CEO of Box, joins Theo Jaffe and Sophia Puccini on MTS to discuss why open models could make the AI ecosystem more competitive, the debate around distillation in China, and why America needs more open-weight AI.

September 5, 2026

Gavin Baker: Why AI Demand Is Outrunning Compute Supply

In this episode, David George and Gavin Baker discuss the economic implications of the AI boom, exploring why AI might be a positive-sum market and the sustainability of the current build-out, including the challenges of compute supply and the potential for asteroid mining.

August 31, 2026

Why a16z Launched the Machine Age Fund | Jen Kha

Jen Kha, Managing Partner and Head of Global Partnerships at a16z, discusses the firm's new $1.1 billion Machine Age Fund, focusing on the physical infrastructure underpinning AI and why this area is becoming a national priority.

August 30, 2026

Why 1,200 AI Agents Started Working Together | Ryan Greenblatt

Ryan Greenblatt, Chief Scientist at Redwood Research, joins Theo Jaffe on MTS to unpack a new investigation into the Open AI Hugging Face hacking incident. Researchers found agents building message boards, forming teams, assigning each other tasks, trading favors, and in some cases, sacrificing their own chances of success to help the broader group.

August 29, 2026

The Infrastructure Behind the Machine Age

Ben Horowitz, Raghu Raghuram, and Martin Casado discuss the launch of a16z's Machine Age Fund, dedicated to the infrastructure powering the next era of AI.

August 28, 2026

Inside Cursor: The Anatomy of a Generational Startup

Cursor's founders, Martin Casado, Sarah Wang, and Matt Bornstein, discuss the decisions that shaped the company from its earliest days, building a standalone product instead of a plugin, resisting the push into enterprise sales too early, and staying relentlessly focused even as the competitive landscape changed around them.

August 27, 2026